GSE77964   Details

GSE Accession GSE77964
Title Expression Patterns of Non-Alcoholic Fatty Liver Disease genes and Efficacy of Green Tea on Hyperlipidemic Animal Model
Submission Date 2/16/16
Last Update Date 1/1/17
Pubmed ID
Experiment Type Expression profiling by array
Contributor Mohammed,A,Alshawsh; Zahurin Mohamed; Shamsul Mohd Zain; Sanaz Koosha; Atefeh Seyyedan; Adaikalavan Ramasamy; Nik,R,Nik Mustapha; Rosmawati Mohamed
Contact Name
Contact E-mail
Organization Name
Country
Organism Mus musculus
Organism ID 10090
Organism Synonym house mouse; mouse
Summary Currently, there are no established treatments for NAFLD/NASH. Treatment recommendations include weight reduction through both diet and physical exercise, and weight-loss surgery for extreme obesity. Most medical regimens target components of the metabolic syndrome or oxidative stress associated with the pathogenesis of NASH. These include anti-obesity regimens, insulin sensitizers, anti-hyperlipidemics, and antioxidants. Thus, a need exists to validate approaches that might help the development and progression of hepatic steatosis, oxidative stress, and inflammation in association with NAFLD.
Overall Design Total RNA was extracted from liver tissues of treated and untreated (NAFLD) groups and submitted for whole genome expression analysis.
Platform ID
Timepoint Count 0
Timepoints []
Disease
Disease ID