GSE35710   Details

GSE Accession GSE35710
Title Human s.c adipose tissue gene expression during diet-induced weight loss
Submission Date 2012-02-10
Last Update Date 2013-04-17
Pubmed ID 23264395
Experiment Type Expression profiling by array
Contributor Anders,,Gummesson; Peter Jacobson; Margareta JernĂĽs; Kajsa SjĂśholm; Intawat Nookaew; Per-Arne Svensson; Lars SjĂśstrĂśm; Lena,M,Carlsson
Contact Name Intawat Nookaew
Contact E-mail
Organization Name Chalmers University of Technology
Country Sweden
Organism Homo sapiens
Organism ID
Organism Synonym man;human
Summary Obesity has considerable effects on morbidity and mortality and the prevalence of obesity has been increasing rapidly worldwide during the past two decades. Even if obesity affects the entire individual, adipose tissue play a central role in the development of obesity. Expression profiling of adipose tissue may give insights into mechanisms contributing to obesity and obesity-related disorders.; 24 obese subjects (6 women and 18 men, BMI 37.6 Âą 4.9) received a very low calorie diet (450 kcal/d, Cambridge diet or Modifast) for 16 weeks. On average, patients lost 27.7 kg during the diet.
Overall Design Microarray expression analysis (Affymetrix U133A) in subcutaneous adipose tissue was performed before diet and after 16 weeks of diet.
Platform ID
Timepoint Count 0
Timepoints []
Disease obesity;
thrombocytopenia-absent radius syndrome;
congenital disorder;
Disease ID 9970;