GSE12289   Details

GSE Accession GSE12289
Title Identifying Significant Temporal Variation in Time Course Microarray Data Without Replicates
Submission Date 2008-07-30
Last Update Date 2012-11-06
Pubmed ID 19323838
Experiment Type Expression profiling by array
Contributor Stephen,,Billups; Margaret,C,Neville; Michael Rudolph; Weston Porter; Pepper Schedin
Contact Name Michael,C,Rudolph
Contact E-mail michael.rudolph@uchsc.edu
Organization Name UCHSC at Fitzsimons
Country USA
Organism Rattus norvegicus
Organism ID
Organism Synonym brown rat;rat;rats;Norway rat
Summary An important component of time course microarray studies is the identification of genes that demonstrate significant time-dependent variation in their expression levels. Until recently available methods for performing such significance tests required replicates of individual time points. This paper describes a replicate-free method that was developed as part of a study of the estrous cycle in the rat mammary gland in which no replicate data was collected.; ; Keywords: developmental time course (time series) throughout the estrus cycle in rat mammary gland singlet data
Overall Design Key points are examined in a time series over the four day estrus cycle of rat mammary gland in virgin (null parous). Singlet rats at each time point were used for mathematical analysis in this study for a total of 31 individual arrays.
Platform ID
Timepoint Count 32
Timepoints gsm: [7 hours, 7.5 hours, 10 hours, 13 hours, 13.2 hours, 14.6 hours, 16 hours, 17.6 hours, 31.6 hours, 32.8 hours, 34.5 hours, 35.5 hours, 37.1 hours, 38.3 hours, 40 hours, 41.6 hours, 43 hours, 57 hours, 58 hours, 59.8 hours, 61.3 hours, 62.5 hours, 64.2 hours, 65.6 hours, 67.1 hours, 79.3 hours, 80.9 hours, 82.5 hours, 83.9 hours, 85.3 hours, 86.3 hours, 88.1 hours]
Disease thrombocytopenia-absent radius syndrome;
congenital disorder;
thrombocytopenia
Disease ID 14699;
759;
1588